Commonwealth Informatics

Commonwealth Federal Services: Supporting Government Agencies in Public Health, Drug safety and Healthcare Research

Commonwealth is on GSA Information Technology (IT) Schedule 70 and is a registered contractor in SAM. Commonwealth has been collaborating with the Federal Government on a variety of projects over the past five years with agencies including the Food and Drug Administration (FDA), Department of Defense (DOD), Center for Disease Control (CDC) and the National Institutes of Health (NIH). Examples of current and prior projects are described below.

  • Research Collaboration Agreement (RCA) – The focus of the agreement is to enhance the Commonwealth Clinical Data Analytics™ (CCDA) platform for analyzing drug safety data. To learn more, read the press release.
  • Safety Support and Consulting Services – Commonwealth was awarded a contract to provide consulting services and technical assistance to the FDA Center for Drug Evaluation and Research  (CDER) and Center for Biologics Evaluation and Research (CBER). To learn more, read the press release. 

  • Development of Remediation Oriented Cohort Builder  – Commonwealth is developing a web-based application to support healthcare quality improvement in the Military Health System under a Phase II Small Business Innovation Research Contract from the Defense Health Program.
  • Application of Cohort Builder for Pharmacovigilance and Drug Utilization Monitoring  – Under a Phase III SBIR Contract,  Commonwealth is extending and customizing its Cohort Builder technology to support the mission of the  Army Pharmacovigilance Center (PVC).  This project includes Drug Utilization monitoring and use of visual analytic capabilities to support pharmacovigilance safety studies. An example from the project is shown in this poster presented at the 2015 OHDSI Symposium: Visual Analysis of Complex Adverse Drug Reactions in Claims Data. 
  • Antibiotic Study Support for Armed Forces Health Surveillance Center –  Commonwealth is responsible for the collection and reporting of MHS  antibiotic usage data in support of the National Healthcare Safety Network.


Quality-Related eMeasures from EHR Data –   In this CDC funded project, Commonwealth extended the EHR Support for Public Health (ESP) open source surveillance platform to implement a chlamydia screening eMeasure based on electronic healthcare records.  Commonwealth worked with an existing ESP site to evaluate the sensitivity/specificity of the newly implemented eMeasure.


Transitioning Electronic Support for Public Health (ESP) from Lab to Marketplace –  The goals of this NIH-funded project are to realize the full functional potential of the open source ESP platform.  Specific aims include making ESP more robust and easier to use and to deploy, and developing additional algorithms for detection and reporting of notifiable diseases.